Spotlights

Launch of Expedite Service


On 19 April and 3 May 2010, 1st BASE launches Expedite Service in Singapore and Malaysia respectively.

This new service aims to bring greater convenience to researchers who are rushing for time to complete their work. At a nominal charge, customers can enjoy the benefit of having orders processed and delivered on priority basis.

This service is applicable for online orders of 1st BASE Oligonucleotide Synthesis and DNA Sequencing services, subject to order requirements.


For more information, log in to 1oo or download our flyers -- Singapore, Malaysia

Services Launch


At 1st BASE, we constantly innovate and develop new technologies to help researchers in their work. One of our major initiatives in 2010 is the Next-Generation Sequencing (NGS) and 1st BASE Custom Research Services.

In the field of genomics, NGS is the driving growth and is revolutionising the way scientists think about their research. May it be ChIP-Seq, Methylation analysis, Genome re-sequencing, the choices are unlimited. We can help you realise your NGS goals.

And for those who are looking for a start-to-finish solution to their research requirements, there is the 1st BASE Research Services. From DNA Cloning to Molecular Genetics and Genomics, we help maximise your success through delivery reliable and high quality data.

Don't get bogged down, make the choice and contact us today!


Download our flyer here

1oo - Biochemicals / Ready-to-Use Buffers


Shop online for 1st BASE Biochemicals and Ready-to-Use Buffers...

From now onwards, you can purchase our wide range of biochemicals/buffers from 1oo, 1st BASE Online Order system. With this enhanced feature on 1oo, you can:

(a) retrieve detailed product information/description; and
(b) request for an official quotation before confirming your order

For current 1oo users, simply order using your log-in ID. For new users, register with 1oo today!

1st BASE Ready-Mix Sequencing Services


Running out of options to cut your reseach costs further ???

1st BASE Ready Mix Reaction Sequencing Service Is Your Solution!

At no more than S$14 per sample, you get quality results at affordable prices.

Features:
(1) Total control on how you mix primer and template;
(2) Daily sample collection;
(3) Results emailed in 3 working days;
(4) Pre-made universal primers at S$10 per tube; and
(5) Industry leading technical support and consulation

Download our flyer here

Product Launch - 1st BASE Fragment Analysis Service


From November 2009, we offer DNA Fragment Analysis service where fluorescently labeled fragments are detected using Applied Biosystems® Genetic Analyzer and interpreted using GeneMapper v4.0 analysis software.

Key Features:
* Fragments within 50bp and 500bp may be sized to within 1 nucleotide resolution
* Supported dyes - Dye Sets D and G5
* Labeled primers may be ordered with 1st BASE. Refer here for DNA Synthesis ordering information
* Spectral Optimisation Service available to optimize loading of samples for optimal signal strength for data analysis

For more information, please click here .

Alternatively, you may contact our local sales office at:-
Singaporesequencing-sg@base-asia.com
Malaysiasequencing-my@base-asia.com
Internationalsequencing@base-asia.com

Published & Validated siRNA by 1st BASE!!!


With effect from 1 March 2008, researchers can now select from a wide range of 1st BASE Published & Validated siRNA. All siRNA duplex are HPLC purified (97% purity) and have shown to suppress corresponding gene expression. The list of Published & Validated siRNA gene is as follows:-

Gene Name
CHO1
corin, mouse
Cyclin B1
Cyclin B2
Cytoplasmic Dynein 1 Heavy Chain
DCC interacting protein ( DIP13-alpha)
Dishevelled (hDv-1 and hDv-3)
Eg5
Emerin
Eve
Fortilin
GalTII (galactosyltransferase II)
GAS41 (1)
hDv-2
Hec-1
hFbw7 (cyclin E ubiquitination)
HPV E6
HPV E7
hRad9
HtrA2
keratin 18
hKIS (Kinase interacting stathmin)
Lamin A
Lamin A/C
Lamin B1
Lamin B2
LAP2
Mad1
MSF (Mammalian septin)
MeCP2 (Methyl-CpG-binding protein 2)
MBD2 (Methyl-DpG binding domain protein 2)
hMps1 (MPS1 kinase)
MCL1 (Myeloid cell leukemia protein 1)
Nct (Nicastrin)
NuMA
Nup153
P160 ROCK
hP1k1 (Polo-like Kinase1)
PKR (Protein Kinase Receptor)
Rad17
hTF (Tissue Factor)
Vimentin

Place your orders at oligo-sg@base-asia.com with your target gene name.
Custom made siRNA duplex is also available, please enquire for more details

1st BASE, Singapore launches an Accelerated 8-week PAb Production Service - at Great Prices too!


Features of Anti-sera Production Project
  1. Free Design Assistance and Antigenicity Analysis for Peptide Antibody projects.
  2. Two New Zealand White (female) rabbits will be immunized for each immunogen
  3. Accelerated eight-week immunization schedule New!
  4. Four boosts and a single ELISA testing are included in our standard programme
  5. Three production bleeds per rabbit for a final total yield of around 150ml

8-week Anti-sera Production Schedule (Accelerated Schedule)

Week Procedure
0 · Pre-immunization bleed:
To collect 5mL of pre-immune serum (negative control) per rabbit

· Primary immunization:
Each rabbit is injected with 200 µg of antigen emulsified in Complete Freund's Adjuvant (CFA)
2 · Immunization No. 2:
100 ng antigen per rabbit in Incomplete Freund's Adjuvant (IFA)
4 · Immunization No. 3:
100 ng antigen per rabbit in Incomplete Freund's Adjuvant (IFA)
5 · Production Bleed No. 1:
25mL serum per rabbit
6 · Immunization No. 4:
100 ng antigen per rabbit in Incomplete Freund's Adjuvant (IFA)
7 · Production Bleed No. 2:
25mL serum per rabbit ELISA Testing and Reporting
8 · Production Bleed No. 3:
25mL serum per rabbit (terminal bleed)

Please download and fill in our Order Form and send in your order request to:

Singapore Malaysia International
antibody-sg@base-asia.com info-my@base-asia.com info@base-asia.com

Gene Synthesis Service by 1st BASE


Custom Gene Synthesis is a cost-efficient approach to generate your Construct.
A rapid turnaround time with 100% fidelity guarantee, Custom Gene Synthesis is a smart and attractive option to complement your Molecular Cloning needs!

1st BASE Gene Synthesis Service includes:
  1. dsDNA Supplied in pBluescript II SK(+) plasmids (2x10 μg)
  2. Sequence report, including complete sequencing and sequence chromatograms
  3. All sequence data keep in full confidence.

To enquire, please provide details on the name of your project, the full sequence required, and identity of your choice of vector and RE sites to use. 1st BASE will do a quick review of the sequence and Quote!

Send us your Sequence and Project details today.

Singapore Malaysia International
oligo-sg@base-asia.com oligo-my@base-asia.com oligo@base-asia.com

1st BASE, Malaysia now boasts of ABI 3730 Genetic Analyzers - bringing unbeatable DNA Sequencing Services to You!


Features of our DNA Sequencing Services:
  1. An Improved Analysis system and software allows:
    1. Superior Resolution of Reads
    2. Up to 60% increased Read Lengths
    3. Lower sample requirements
  2. An unbeatable throughput and turnaround time in all of Malaysia
  3. Industry-leading technical support and customer service.

Do not settle for anything less. Send us your samples today.

Take advantage of our electronic order form to facilitate faster processing, see here for ordering details.